When the adventurer Allan Quartermain is asked by Sir Henry Curtis and Captain Good to help them find Sir Henry's missing brother, who was last seen trekking into the remote African interior in search of the fabled King Solomon's Mines, he reluctantly agrees, yet fears that there is little hope of coming back alive.

Following a map drawn in blood, the men cross vast deserts and scale snow-covered mountain peaks, facing fearful dangers and hardships, until they reach Kukuanaland, where they meet their greatest peril yet...