A masterful survey of the history of Marxist philosophy of science Sheehan retraces the development of a Marxist philosophy of science through detailed and highly readable accounts of the debates that shaped it. Skilfully deploying a large cast of characters, Sheehan shows how Marx and Engel's ideas on the development and structure of natural science had a crucial impact on the work of early twentieth-century natural philosophers, historians of science, and natural scientists. With a new afterword by the author.