This book aims to educate the public and medical personnel about the importance of newborn screening and to compile and disseminate the results and history of newborn screening in Taiwan over the past 30 years. In addition, it aims to disseminate the knowledge of congenital metabolic disorders to the public in hopes to encourage individuals to take action in the direction of participating in newborn screening and provide care and assistance to each other. The book is outlined as follows: 1. Chapter One: Taiwan’s determination in the beginning of promoting newborn screening. 2. Chapter Two: Historical background for promoting newborn screening. 3. Chapter Three: Establishment of the newborn screening system (inclusive of policies and comprehensive screening service). 4. Chapter Four: Transformation from the first-generation newborn screening to the second-generation & the second-generation newborn screening contents. 5. Chapter Five: International exchange of newborn screening policies and quality control experiences. 6. Chapter Six: Achievements in newborn screening of the past 30 years.