Today's philosophy of knowledge usually takes into consideration only two leading components: the material world in which we live, and the ideal world of the human brain. They contradict and, at the same time, complement each other, while their cooperation creates new knowledge and its practical implications. This book propounds quite a different conception of producing new ideas, and introduces onto the scene the semiotic reality: signs and sign systems (progenies of human mind). According to this view, the material world is transformed in our mind, where it receives its sign vesture. Then, it can be explained and understood by various audiences, and enters the depository of human wisdom.As the book shows, the interplay of the three realities (ontological, semiotic and virtual) gives rise to many new notions, like metathinking and the second scientific period of our civilization, among others.