When rock star Dazzler walked out on S.H.I.E.L.D., she hoped she'd seen the last of the clandestine organization. But when a rogue agent drops in after a sold-out gig, she must decide whether to work with them again or stick to her solo career. The agent links Mutant Growth Hormone - a dangerous biochemical that wildly enhances mutant powers - with the disappearance of Magneto and Cyclops. Reluctantly, Dazzler takes the case and unfolds a mystery greater than she anticipated. In need of a new team, she recruits the extraordinary mutants Emma Frost, Polaris, and Rachel Grey on a mission to foil a plot to remove mutantkind forever, which blasts them from Earth into a whole new dimension.