This book offers an account of US fiction during a period demarcated by two traumatic moments: the eve of the entry of the United States into the Second World War and the onset of the Covid-19 pandemic. The aftermath of the Second World War was arguably the high point of US nationalism, but in the years that followed, US writers would increasingly explore the possibility that US democracy was a failure, both at home and abroad. For so many of the writers whose work this volume explores, the idea of "nation" became suspect as did the idea of "national literature" as the foundation for US writing. Looking at post-1940s writing, the literary historian might well chart a movement within literary cultures away from nationalism and toward what we would call "cosmopolitanism," a perspective that fosters conversations between the occupants of different cultural spaces and that regards difference as an opportunity to be embraced rather than a problem to be solved. During this period, the novel has had significant competition for the US public's attention from other forms of narrative and media: film, television, comic books, videogames, and the internet and the various forms of social media that it spawned. If, however, the novel becomes a "residual" form during this period, it is by no means archaic. The novel has been reinvigorated over the past eighty years by its encounters with both emergent forms (such as film, television, comic books, and digital media) and the emergent voices typically associated with multiculturalism in the United States.