The book has imperative and up-to-date information on the basics to advanced therapeutic approaches against various life-threatening diseases including vector and parasite-borne diseases, COVID-19, Mucormycosis, and cancer as well. The book harbors extensive knowledge about the applications and effective utilization of advanced personalized medicines, target-based nanoencapsulated phytochemicals, and herbal nanomedicines against life-threatening diseases including cancer, thereby having implications in the cancer biology field encompassing pharmaceutical and life science sectors considerably. Moreover, the proposed book would provide a strong platform for delineating the complex mechanism underlying the disease therapeutics along with the potential therapies countering the existing menace of drug resistance, especially concerning cancer. More so the book will showcase the recent advances in the use of nanocomposite films and molecular-mediated drug delivery for therapeutic applications. The uniqueness of this book is to provide all the possible information from basics to advanced nano-therapeutics at a single platform making it a valuable informative source to the graduates of various universities across the globe to understand multifaceted therapeutic applications against life-threatening diseases. The book is an outstanding compilation comprising comprehensive information on therapeutic advances at a single platform. The book is apt to the present needs and well aligned with the offered curricula in Universities across the globe for UG, PG, and Ph.D. programs encompassing life sciences, medical, paramedical, and pharmaceutical courses. The diversity of chapters in the book are going to covers various aspects of the parasites, pathophysiology, and pathogenesis along with the pivotal role of nanotechnology in drug discovery and nano-biosensors for the detection of coronavirus as well. Moreover, the book has interesting elements of futuristic personalized medicines in combating coronavirus along with remedial therapeutic measures against coronavirus-induced mucormycosis. Another chapter deals with multifaceted therapeutic advances in life-threatening human diseases from traditional, complementary, and integrative medicine to nano-based targeted drug delivery. In the end, the authors have shed light on understanding oncogenesis and cancer and finding an amicable therapeutic nanomedicine solution paving the way towards individualized medicine therapeutics against cancer. With the advent of newer technologies such as combinatorial chemistry high-throughput screening, next generation sequencing, it is now possible to consider that nanotherapeutics and personalized medicines could be the sound death knell for a variety of dreadful diseases including cancer and also to deal with the growing menace of drug-resistance. Once again, our sincere thanks to all the contributing authors who worked like a team to let us complete this book. Special thanks to the Editorial team of the publishing house who were available all the time to impart their valuable input and assistance. Words of appreciation also go to the whole Production Team as well.