This book presents data and discusses the results of research conducted on crack cocaine consumption and other drug use in the city of Sao Paulo, Brazil, specifically in the area commonly referred to as "Cracolandia" ("Crackland"). This context is marked by high social vulnerability, rife with numerous inequalities, violence, and human rights violations. The work describes the living conditions of individuals in this setting, narrating their social trajectories, urban itineraries, motivations for substance use, perspectives, and life projects.The book provokes a crucial debate concerning the iatrogenic effects resulting from prohibitionist-repressive "war on drugs" policies. It highlights potential alternative paths for formulating and implementing public policies and psychosocial interventions.'Amidst the Flow' serves as a valuable resource for researchers and professionals in the fields of addiction studies, healthcare, sociology, law, and drug policy-making. It presents a compelling call for a paradigm shift in drug policies.